Here is the solution for that. . .

Please go step by step because its very risky. . .
... Go to RUN
- Type regedit
- Then go to HKEY_LOCAL_MACHINE (don’t click on it just click on (+)
- Then go to SYSTEM
- Then go to CurrentControSet
- Then go to Services
- Then “click” on USBSTOR
- Now change the value of REG_DWORD
- You have to put the value 4 in place of 3. . .
You will success fully disable your USB port . . .

For enabling the USB port
- You have to put the value 3 in place of 4. . .